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Doubling the duration of adjuvant tamoxifen treatment in women estrogen receptor (ER)-positive breast cancer reduces risk of late recurrence and death compared with the current standard-of-care of 5 years' therapy. So say the results of a large international randomized trial presented at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium and simultaneously published in The Lancet.

The New York Times claims that today, about 39% of doctors nationwide are independent, down from 57% in 2000, citing estimates by the consulting firm Accenture. The article "A Hospital War Reflects a Bind for Doctors in the U.S.," which appeared on the New York Times web site on November 30, 2012, discusses the state of healthcare in Boise, Idaho, which the authors call "a medical battleground" and claim is representative of the healthcare situation in many cities around the United States.

Researchers in the United Kingdom have found an increased prevalence of asthma among children born to parents who used assisted reproductive technologies (ART). A large registry-based study conducted by researchers at the University of Oxford and the University of Essex in England drew from the Millennium Cohort Study, a UK-wide, prospective study of 18,818 children recruited at age 9 months.

A National Institutes of Health-funded study published in the Journal of Biochemical and Molecular Toxicology provides evidence that exposure to the compound bisphenol A (BPA) during human pregnancy is considerable, and that elimination of BPA occurs more slowly in fetuses than in adults.

A mouse model suggests that prenatal treatment with neuroprotective peptides may have potential in improving learning performance in Down syndrome, according to researchers from the National Institute of Child Health and Human Development (NICHD).

Sleep apnea affects women and men differently because of sex-specific changes in the brain. This is the finding of researchers at the University of California at Los Angeles (UCLA)'s School of Nursing, School of Medicine, and Brain Research Institute.

Prostaglandin inhibitors, such as celecoxib and indomethacin, and calcium channel blockers, such as nifedipine and nicardipine, had the highest probability of delaying premature labor by 48 hours and improving maternal and neonatal outcomes, according to a systematic review and network meta-analysis published in a recent issue of BMJ.

Fear-not clinical indications-may be the driving force in women's decision-making about contralateral prophylactic mastectomy (CPM). That is the surprising conclusion from a population-based study presented by investigators from Michigan at the 2012 American Society of Clinical Oncology (ASCO) Quality Symposium in San Diego.

The 2011 US birth rate was the lowest ever recorded, according to a report by the Pew Research Center for its Social & Demographic Trends project. The decline was greatest in births to immigrant women.

Long-acting reversible contraceptives (LARCs) are not only highly effective, they are appropriate under a variety of conditions. Here, the authors present 3 scenarios in which patients would benefit from LARC methods.

A child whose mother experienced influenza or prolonged fever or was prescribed antibiotics for common infections while pregnant may be at an increased risk of autism spectrum disorder (ASD).

The sexual functioning, experiences, and behaviors of couples as they undergo assisted reproductive technology (ART) procedures have rarely been explored, according to researchers at Indiana University in Bloomington, Indiana.

In a commentary presented at the European Congress of Perinatal Medicine in Paris in June 2012, researchers from the United States, the United Kingdom, and Germany urged obstetric providers to discourage promoting home births as safe alternatives to births in hospitals.

Taking selective serotonin reuptake inhibitors (SSRIs) during pregnancy may put women at risk of miscarriage and preterm birth (PTB) and also put their babies at risk of a number of health and developmental complications, according to a recent study.