March 21st 2024
GlaxoSmithKline's phase 3 trial demonstrated promising overall and progression-free survival outcomes in patients with primary advanced or recurrent endometrial cancer, paving the way for potential FDA approval.
New gene linked to breast cancer risk
August 14th 2014Mutations in the PALB2 gene may be associated with a significant increase in the risk of breast cancer, according to a recent study in The New England Journal of Medicine. PALB2 binds to BRCA2-a gene that confers increased lifetime risk of developing breast or ovarian cancer-and likely permits its stable nuclear localization and accumulation.
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New light on prevalence of uterine cancer in morcellation cases
July 31st 2014An analysis of minimally invasive hysterectomies performed at multiple institutions over a 7-year period shows that one in every 368 women who underwent morcellation had uterine cancer. According to the investigators, the study also reveals an association between advanced age and increasing prevalence of underlying cancer and endometrial hyperplasia in these patients.
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Black women at higher risk of triple-negative breast cancer
May 29th 2014A new analysis of data from a nationwide hospital-based dataset shows that black women have higher odds of being diagnosed with triple-negative breast cancer-a subtype associated with poorer prognosis-than do white women, regardless of socioeconomic status (SES). The report was published in the June issue of Breast Cancer Research and Treatment.
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WHI report says physical activity may help prevent death due to ovarian cancer
May 8th 2014Women who engage in vigorous physical activity before a diagnosis of ovarian cancer may be at lower risk of dying of the disease, according to a new report by investigators from the Women’s Health Initiative (WHI).
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