Gynecologic Oncology

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Among BRCA mutation carriers, risk-reducing bilateral salpingo-oophorectomy (RRSO) results in an 80% reduction in risk of ovarian cancer and a 50% reduction in risk of breast cancer if the surgery is performed before the onset of menopause.

An ADP-ribose polymerase (PARP) inhibitor has received accelerated approval from the US Food and Drug Administration (FDA) for treatment of women with heavily pretreated ovarian cancer associated with defective BRCA genes.

Women at risk of ovarian cancer and who are undergoing hysterectomy should be counseled about the possible benefits of salpingectomy, according to a new committee opinion from the American College of Obstetricians and Gynecologists.

FDA approves Gardasil 9

On December 10, 2014, the US Food and Drug Administration (FDA) approved Gardasil 9 (Human Papillomavirus [HPV] 9-valent Vaccine, Recombinant) for the prevention of certain diseases caused by 9 types of HPV.

Studies of the impact of diet on risk of ovarian cancer are limited and their results unclear but a new report based on data from the Nurses’ Health Study (NHS) suggests a possible association between high intake of flavonoids and black tea and lower risk of the disease.

cfDNA gives insight into the pathogenesis of serious disease and early information about benign conditions.