Vulvovaginal Disease

Variation in outcome reporting and measurement tools among treatment trials for GSM

August 28, 2020

Considerable heterogeneity exists in reported outcomes and measures used in clinical trials of treatments for genitourinary syndrome of menopause (GSM), which impacts between 40% and 60% of postmenopausal women, according to a systematic review in the journal Menopause.

Too many teen pelvic exams and Pap tests?

July 10, 2020

Results of a nationally representative study indicate that many young women receive bimanual pelvic exams (BPEs) and Pap tests that may be unnecessary, and not in compliance with the latest guidance from the American College of Obstetricians and Gynecologists (ACOG).

Impact of vulvovaginal atrophy on sexual function in postmenopausal women

May 13, 2020

For postmenopausal women with at least one vulvovaginal atrophy (VVA) symptom, the presence of physician-confirmed VVA is linked to significant impaired sexual function, according to a study from the European Vulvovaginal Epidemiological Survey (EVES).

Vulvovaginal atrophy among breast cancer survivors

May 13, 2020

A diagnosis of vulvovaginal atrophy (VVA) in breast cancer survivors is associated with a significant increase in the burden of illness and social costs, according to an Italian Delphi Panel in the journal Supportive Care in Cancer. These findings are primarily due to a rise in comorbidities and resource utilization, but adequate treatment might reduce the impact of the condition.

Discussing vulvovaginal health at well-woman visits

October 11, 2019

Although nearly half of postmenopausal women reported having vulvovaginal symptoms (VVS), only a minority discussed their symptoms during a well-woman visit with a primary care provider or gynecologist, according to recent survey analysis.

Investigational 17β-estradiol vaginal capsule relieves dyspareunia and vaginal dryness

June 14, 2018

The experimental agent TX-004HR effectively improved the vaginal mucosa of postmenopausal women with vulvovaginal atrophy (VVA) and reduced moderate-to-severe dyspareunia and vaginal dryness compared to placebo, according to results of a trial.

Does laser treatment help vulvovaginal atrophy?

May 15, 2018

A small study shows that treatment with CO2 laser induces histological changes in the epithelium and lamina propria that may result in improvement in symptoms associated with vulvovaginal atrophy (VVA).

Are vaginal estradiol tablets better for VVS than OTC moisturizer or placebo?

March 27, 2018

Results of a randomized clinical trial (RCT) suggest that over-the-counter moisturizer may be just as effective as vaginal estrogen tablets for treatment of vulvovaginal symptoms (VVS) in postmenopausal women. Plus: Does a Mediterranean diet help protect bones in postmenopausal women? Also: Metformin, an oral diabetes medication, seems to reduce the likelihood of late miscarriage and premature birth in women with polycystic ovary syndrome (PCOS), according to results of a multicenter study.