U/S study shows impact of prenatal SSRIs, maternal depression
July 13th 2012Use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy is associated with smaller fetal head circumference-a prenatal marker of brain volume-and with higher risk of preterm birth (< 37 weeks), according to findings from a prospective population-based study from the Netherlands.
Cervical Insufficiency protocol
July 1st 2012In this chapter, Dr. Owen reviews the diagnosis or cervical insufficiency; patient selection for history-indicated (prophylactic), physical examination-indicated (Emergent), and ultrasound-indicated (urgent) cerclage; placement and removal of cerclagel and adjunctive therapies.
FDA approves new treatment for HER2-positive late-stage breast Cancer
June 29th 2012The United States Food and Drug Administration (FDA), under its priority review program, recently approved PerjetaTM (pertuzumab), a HER2/neu receptor antagonist indicated in combination with HerceptinR (trastuzumab), another HER2 therapy, and docetaxel for treatment of HER2-positive metastatic breast cancer (BCa) in women who have not received prior anti-HER2 therapy or chemotherapy for metastatic disease.
FDA finds no major safety issues for compounded 17P
June 29th 2012Analysis by the United States Food and Drug Administration (FDA) of compounded 17α-hydroxyprogesterone caproate (17P) shows the samples meet the potency and total purity standards for Makena, the branded version of the drug. Testing was done on 16 samples of bulk 17P active pharmaceutical ingredients (API) in response to questions from K-V Pharmaceuticals, Makena’s sponsor, about potency and purity of the compounded product.
Hysterectomy Linked With Large Artery Stiffening
June 20th 2012Estrogen-deficient women who have had a hysterectomy with or without ovarian preservation are more likely to have arterial stiffness than estrogen-deficient women who have not had a hysterectomy, according to results of a new study conducted at the University of Colorado School of Medicine in Denver.
Poll: Are You Confident in Your Ablity to Understand Statistical Information?
June 19th 2012Nearly three-quarters of ob/gyn residents were unable to identify the positive predictive value of a screening mammogram on a multiple choice test, yet 80% believed they had adequate training in statistical literacy.
More Countries Report Cephalosporin-Resistant Gonorrhea
June 18th 2012The number of cases of cephalosporin-resistant gonorrhea is increasing, according to a recent report issued by the World Health Organization. Neisseria gonorrhoeae, the bacteria that causes the infection, has already developed resistance to other common antibiotics, and cephalosporins have become the last line of defense against the infection.