
Since their introduction, cervical cytology screening programs have caused a substantial reduction in cervical cancer rates. However, the low sensitivity of one screen and resulting need for repeated screens during a lifetime to achieve programmatic sensitivity has deemed it inefficient. With that in mind, Dr Philip E Castle, of the American Society for Clinical Pathology in Washington, D.C., and colleagues compared the performance of the cobas human papillomavirus (HPV) test versus liquid-based cytology.


