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Suppose for instance, that last year, the chair of an organizing committee invites you to lecture at a meeting. You accept. You then assist this chair in organizing the program by inviting other speakers to the meeting. Two months before the meeting, the invitation for you to speak is withdrawn.

In minimally invasive surgery (MIS), complications can occur due to faulty instruments, surgical technique, or inadequate patient election. Surgeons who routinely perform MIS rarely encounter complications. Conversely, practicing gynecologists at large often find that certain procedures or techniques are not as safe as previously reported in the literature by the "experts." One of the reasons is that complications tend to be underreported.

The tragic events of September 11 have, to put it mildly, thrown many people off balance. On a somewhat secondary scale, our Society was affected. The 5th Regional Meeting of ISGE in conjunction with the 2nd Brazilian Congress of Gynecologic Endoscopy took place on September 12-15, 2001.

We are entering a time in the development of the discipline of gynecologic endoscopy where there is an opportunity to build bridges, both ideologically and functionally. The science and practice of endoscopy have progressed to the point where core groups of advanced endoscopic surgeons have organized themselves in every corner of the world, not only to exchange knowledge, but also to set goals and plan for the future of the field.

Uterine prolapse or dropped womb is a condition in which the uterus drops downward in the pelvis below its normal position. The uterus may drop slightly and remain above the introitus (vaginal opening, grade 1). It may drop further so that the cervix or lower portion of the uterus reach the region of the introitus (grade 2). In the most severe form, the cervix or even the entire uterus bulges out of the introitus (grade 3). Uterine prolapse is the indication for hysterectomy in 16% of cases in the U.S.

Despite the major public health impact of leiomyomas, little is known about their cause. Until recently, the steroid hormones estrogen and progesterone were considered the most important regulators of leiomyoma growth. There is abundant evidence that estrogen promotes fibroid growth including the clinical observations that fibroids grow in the presence of high levels of estrogen, such as during the reproductive years, and that they regress in the presence of low levels of estrogen, such as following menopause or during gonadotropin releasing hormone (GnRH) agonist therapy.

The first laparoscopic hysterectomy was performed in 1989 by Henry Reich. Nowadays the laparoscopic hysterectomy for a uterus up to 300 grams, without other pathologies that could limit its mobility or without a poor vaginal access, has to be considered a basic well standardized procedure.

GnRH-agonists as analogues of the natural GnRH have gained great importance in gynaecological endocrinology and have proven to be particular useful in clinic and practice being applied to treat a large range of clinical conditions. However, the clinical use is negatively influenced by GnRH-agonist induced side effects due to hypoestrogenism, which is the main type of action to be used for treatment and prevention.

Hormone Replacement Therapy: In most European countries, the actual Guideline on the Evaluation of New Medicinal Products in the Treatment of Primary Osteoporosis is incomplete in that, unlike the previous Note for Guidance on Postmenopausal Osteoporosis in Women (EMEA 2001 Guidance), it fails to address the prevention of osteoporosis indication.

The world of menopausal care is changing. For many years, the scientific community involved in menopause research has been amassing evidence that the menopause is associated with multiple complaints and chronic diseases, and that postmenopausal hormone therapy has the potential to prevent or treat most of them.

What are Uterine Fibroids?The walls of the uterus are made of smooth muscle called myometrium, and the inside lining, with glandular tissue, is called endometrium. “Uterine fibroid” is a slang term for leiomyoma, or often simply myoma. Fibroids are benign tumors made of smooth muscle cells.

Based on the protective effects of intrauterine devices against endometrial cancer, researchers hypothesized that IUDs may also have a protective effect against cervical cancer. However, results from epidemiological and clinical studies to date have been inconclusive.

New research sheds light on vulvodynia, showing that the disorder is under-diagnosed and inadequately treated. Since the chronic pain associated with vulvodynia can make it difficult to sit or participate in sexual activity, the disorder greatly impacts quality of life for women afflicted with it. The research is published online as part of the American Journal of Obstetrics and Gynecology.

Hysterectomy is the most frequently performed operation in women, with a life time risk varying from country to country from less than 20% to more than 40%. Overall these differences reflect more medical practice than differences in pathology between countries.

Laser versus Electrosurgery

Both types of surgery are complimentary. Each has specific advantages and indications. It is an advantage to have and to be able to use both.

Menopause and Hormones

Steroid hormones have a typical chemical structure. Their mechanism of action is through binding to a specific receptor which in the nucleus of the cell will induce effects at the genomic level.

Recently a letter was sent to the Women's Health Forum by a patient who had undergone numerous surgeries in an effort to alleviate her pain due to surgical adhesions. Additionally, I recently had a patient whose case demonstrates a rather typical story for post-surgical adhesions, and her management. These two patient cases I hope you will find informative and "food for thought".

Myomectomy is becoming a much more frequently performed procedure certainly it is one that is sought out much more frequently by our patients. Probably the most intimidating form of fibroids is that which occurs in the broad ligament, and particularly one which occurs in the cervical region.

Cancer of the vulva is not a common disease. There are about 4,000 new cases each year in the United States. Although it can occur in women in the third and fourth decade it is usually diagnosed in older women. Over 95% of vulvar cancers arise from the squamous epithelium. The remainder are mostly melanomas. The cause of squamous cancer of the vulva is unknown but there is a weak association with Human Papilloma Virus (HPV). The most important feature about vulvar cancers is the premalignant phase.

Many medical conditions, including all cases of cancer, must be diagnosed by removing a sample of tissue from the patient and sending it to a pathologist for examination. This procedure is called a biopsy, a Greek-derived word that may be loosely translated as "view of the living."

The Society of Gynecologic Oncologists (SGO) has endorsed the American Cancer Society's (ACS) new guidelines, "Early Detection of Cervical Neoplasia and Cancer," released in the Nov./Dec. issue of CA: A Cancer Journal for Clinicians. The new guidelines represent a significant step forward in advising the health care community and the public on the importance of cervical cancer screening and the relationship between the Human Papillomavirus (HPV) virus and cervical cancer.

Depression and incontinence appear to be associated in women, but the statistical strength of that association depends on the instrument used to classify depression, according to this population-based, cross-sectional study. Investigators used data on 5,701 women aged 50 to 69 years collected during interviews conducted for the Health and Retirement Study.