Reducing pregnancy-related infection deaths will require interdisciplinary care protocols, expanded postpartum access points, and broad-based sepsis education across specialties, according to MMRC data showing that most decedents had a health care encounter within 1 week of death.
Azad and colleagues at Columbia University found that drug overdose, homicide, and suicide are the leading causes of death among pregnant and postpartum women.
Adnan I. Qureshi, MD, advocates for the integration of neurologists into obstetric teams to manage the increased stroke risk among pregnant persons with a previous stroke.
Simon highlights the "seamless handoff" between FQHCs and OB hospitalists as a vital mechanism for maintaining delivery access in rural and underserved communities.
A before-and-after cohort study of more than 18,000 patients found that universal aspirin 162 mg dispensation at the first prenatal visit was associated with a 29% reduction in preeclampsia with severe features, with benefit observed across patients with and without chronic hypertension and no increase in hemorrhagic complications.
Adnan I. Qureshi, MD, calls for a multidisciplinary action plan that integrates neurologists into obstetric teams to manage increased recurring stroke risk in pregnancy.
Clinicians evaluating women with new or worsening urinary incontinence should consider thyroid dysfunction—especially hypothyroidism—as a potential contributing factor, with overflow symptoms and systemic hypothyroid signs prompting laboratory evaluation and a comprehensive management approach.
Alla Vash-Margita, MD, FACOG, details how identifying differentially expressed microRNAs in 13- to 26-year-olds could provide a pathway for early detection of endometriosis.
A 4857-patient international RCT found that a single postpartum infusion of IV ferric carboxymaltose was superior to twice-daily oral iron in achieving a non-anemic hemoglobin level at 6 weeks, with sustained hemoglobin benefit through 6 months across all regions studied.
Clinical Case 5 Adjusting Thyroid Replacement Therapy after Discontinuing Estrogen
Clinical Case 4 When/How to test for Hypothyroidism during Menopause
Clinical Case 3 Overtreatment of Hypothyroidism during Menopause
Clinical Case 2 Effect of Estrogen Replacement Therapy on Hypothyroidism
Clinical Case 1 Dietary Supplements
Sangini Sheth, MD, emphasizes that shared decision-making is vital when presenting patients with the choice between clinician-collected and self-collected hrHPV screening options.
Sangini Sheth, MD, MPH, highlights that the updated HRSA guidelines empower patients by offering FDA-approved self-collection options for primary HPV testing.
A case report describes the first known use of low-intensity extracorporeal shock wave therapy for episiotomy scar pain, with a patient reporting meaningful improvement after more than 20 years of chronic pelvic floor dysfunction.
A retrospective study of more than 3200 cesarean deliveries found that patients with three or more prior cesareans have a 15% likelihood of a uterine window, supporting consideration of early-term delivery in this group.
Lam-Rachlin reported that the software did not add time to the examinations and, in some instances, appeared to speed up the process by providing a rapid preliminary analysis.
A national EHR database study found that GLP-1 RA prescribing among perinatal patients increased more than thirtyfold between 2019 and 2024, with an estimated 20,000 pregnant individuals exposed in 2024 alone.
A large preconception cohort study found that nearly 41% of pregnancy planners tested more than 4 days before their expected period, a pattern associated with a fivefold higher risk of false-negative results and threefold higher detection of very early pregnancy losses.
Adnan I. Qureshi, MD, reports that women with a history of stroke have 2-fold higher odds of recurrence during pregnancy and the 6-week postpartum period.
Sara Perelmuter advocates for routine postpartum screening and provider education on lactation-safe therapies when dealing with GSL symptoms.
Yale's Alessandro Santin, MD, emphasizes that "knowing our enemy" through sequencing is a way to identify targetable pathways for rare and aggressive ESS cases.
A large insurance database study found that more than 80% of pregnant patients with depression or anxiety discontinued SSRI/SNRI therapy, which was associated with nearly double the rate of mental health emergencies compared to those who continued treatment.
Sara Perelmuter details how naming Genitourinary Syndrome of Lactation (GSL) is a vital step in addressing the treatment gap in postpartum care.
Alessandro Santin, MD, highlights how POLE and mismatch repair mutations in high-grade ESS create a clinical opportunity for using immune checkpoint inhibitors.
New research from the COEQUaL initiative is examining how clinical counseling, insurance design, and referral patterns shape disparities in uterine fibroid care.
Julia Ordway highlights a case where unregulated testosterone pellets led to a 2-year recovery period.
"It's only when you acquire the type of deep knowledge in the molecular characteristic that you may really identify potential targets," said study investigator Alessandro Santin, MD.
