Obstetrics

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Clinicians should carefully consider using noninvasive prenatal testing (NIPT) for the screening of chromosomal abnormalities in twin pregnancies because the combined positive predictive value (PPV) is limited and the screening efficiency is not stable, according to a prospective study.

Despite the inadvisability of performing early amniocentesis (EA) before 15 gestational weeks due to a high rate of miscarriage, a retrospective cohort study has found no significant difference in the procedure-related risk of miscarriage between EA, at around 14 weeks gestation, and mid-trimester amniocentesis (MA).

Despite the umbilical artery (UA) Doppler pulsatility index being used to detect elevated fetoplacental vascular resistance, the metric is confounded by variation in fetal cardiac function and is only moderately predictive of placental pathology.

Although fortification of expressed breast milk (EBM) via commercially available human milk fortifiers (HMF) has been shown to increase short-term weight and length among preterm very low-birth-weight (VLMW) neonates, widespread adoption of HMF is hampered by high cost and the increased risk of severe adverse events.

This list was compiled by Christine R. Isaacs, MD; and William M. Leininger, MD, as a supplement to their presentation from the 2021 American College for Obstetricians and Gynecologists (ACOG) Annual Clinical and Scientific Meeting (ACSM), held virtually April 30-May 2.

“My research centers on examining the intersection of policy, health and economics. In no other area of medicine is policy as critical to health as ob/gyn. It is essential to understand how policy can promote health, or perpetuate reproductive health disparities,” said principal investigator Maria Rodriguez, MD, MPH, an associate professor of ob/gyn in the Section of Family Planning at Oregon Health & Science University in Portland.