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Cutting-edge medical advances and innovative technologies have made headlines and continue to flourish in the new millennium. However, these medical achievements stand in stark contrast to the paradoxical increase in US maternal mortality, which is among the highest of all developed nations.

An updated review of evidence by the US Food and Drug Administration (FDA) underscores concerns expressed in 2014 by the agency about use of laparoscopic power morcellators (LPM) for treatment of uterine fibroids. Plus: Prescription habits show ob/gyns not well informed about opioids, according to a study. Also: Does ADHD medication use during pregnancy increase risk of congenital malformations?

Results of a prospective cohort study by Danish investigators suggest that current or recent use of hormonal contraceptives may be associated with an increased risk of breast cancer. Plus, Editorial Board Member, Ilana Cass, MD, weighs in on the impact of the study's findings.

Three Phase 1 human clinical trials evaluating the efficacy of an Army-developed Zika purified inactivated virus (ZPIV) vaccine have shown it to be safe and well tolerated, according to a recent study. Plus: Another study has found an association between postmenopausal vasomotor symptoms (VMS), including hot flashes and night sweats, and elevated risk of diabetes.

A multinational randomized controlled trial indicates, for what may be the first time, that continuous glucose monitoring (CGM) may have health benefits that go well beyond control of maternal hyperglycemia. Plus: Does postmenopausal HT impact risk of stroke? Also: A study suggests that late puberty affects bone mineral density.

A recently published meta-analysis has found a relationship between a woman’s vitamin D levels and the success rate of assisted reproduction therapy (ART). Plus: Is progesterone effective in preventing preterm birth? Also: Results of a large cohort study show that women whose BMI is below or above normal before pregnancy may be at increased risk of complications or death associated with birth.

The large body of evidence citing the effectiveness of IVF and recent advances promoting the safety of ART, including the widespread adoption of SET, have established IVF as a reasonable first-line alternative for many infertile couples rather than the treatment of last resort it was once regarded.

According to a study, a pregnant woman’s use of acetaminophen may be associated with increased risk of her child developing attention-deficit/hyperactivity disorder (ADHD). Plus: Another study says race is sole indicator of breast reconstruction likelihood. Also: FDA issues guidance on labeling for surgical aspirators.